This is an incredible question. The first thing I would state is just be honest about the change. A hiring manager will want to know why…so if you can address that in a cover letter I would highly recommend it. You always want to anticipate the hiring manager’s questions and/or concerns and address them up front. Some ways you can do this in the situation you have mentioned:

First: In this instance it is going to be critical you write a cover letter explaining your change in career. Talk to your passion and why you are so excited to get back into your old field of work.
Second: In your cover letter be sure to relate how your excitement, your passion, and the experience you gained in your other field will relay to the job you are applying for.
Third: You may want to create something called a ‘functional’ resume, which groups your experiences according to categories.

I hope this helps – perhaps a new article idea for our team is how to write a powerful functional resume!

Angela